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Q. No.What is not true regarding Phenylketonuria?
1.
It is an inborn error of metabolism.
2.
It is inherited as an autosomal recessive trait.
3.
The affected individual lacks an enzyme that converts the amino acid tyrosine into phenylalanine.
4.
Accumulation of phenylpyruvic acid in brain results in mental retardation.
Subtopic: Mendelian Disorders |
82%
Level 1: 80%+
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Consider the two statements:
| Statement I: | Thalassemia is a qualitative problem of synthesising an incorrectly functioning globin. |
| Statement II: | Sickle cell anaemia is a quantitative problem of synthesising too few globin molecules. |
1. Statement I is correct; Statement II is correct
2. Statement I is correct; Statement II is incorrect
3. Statement I is incorrect; Statement II is correct
4. Statement I is incorrect; Statement II is incorrect
Subtopic: Mendelian Disorders: Thalassemia |
81%
Level 1: 80%+
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Turner’s Syndrome:
| I: | is an aneuploidy |
| II: | causes infertility in affected females |
| III: | does not affect the development of secondary sexual characters in affected females |
1. Only I and II are correct
2. Only I and III are correct
3. Only II and III are correct
4. I, II and III are correct
Subtopic: Sex Aneuploidy - Turner & Klinefelter Syndrome |
83%
Level 1: 80%+
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In Pisum sativum, the flower position may be axial (allele A) or terminal (allela a). What would be the percentage of the offspring with respect to axial flower position, if a cross is made between parents \(Aa \times aa\) ?
1. 25%
2. 50%
3. 75%
4. 100%
1. 25%
2. 50%
3. 75%
4. 100%
Subtopic: Monohybrid Cross: Further Understanding |
86%
Level 1: 80%+
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In humans, rolling of tongue is an autosomal dominant trait (R). In a family both the parents have the trait of rolling tongue but their daughter does not show the trait, whereas the sons have the trait of rolling of tongue.
The genotypes of the family would be:
The genotypes of the family would be:
| Mother | Father | Daughter | Son | |
| 1. | Rr | Rr | rr | rr |
| 2. | Rr | Rr | rr | RR |
| 3. | rr | Rr | RR | rr |
| 4. | RR | rr | Rr | Rr |
Subtopic: Pedigree Analysis: More Examples |
83%
Level 1: 80%+
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Study the pedigree analysis of human given below and identify the type of inheritance along with an example :
1. Sex-linked recessive, Haemophilia
2. Sex-linked dominant, Vitamin D resistant rickets
3. Autosomal recessive, Sickle-cell anaemia
4. Autosomal dominant, Myotonic dystrophy
1. Sex-linked recessive, Haemophilia
2. Sex-linked dominant, Vitamin D resistant rickets
3. Autosomal recessive, Sickle-cell anaemia
4. Autosomal dominant, Myotonic dystrophy
Subtopic: Pedigree Analysis: More Examples |
67%
Level 2: 60%+
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Possibility of the blood groups of the children in a family where the father is heterozygous for blood group 'A' and the mother is heterozygous for blood group 'B', would be :
1. Blood groups 'A','B'
2. Blood groups 'A','B','O'
3. Blood groups 'AB','O'
4. Blood groups 'A','B','AB','O'
1. Blood groups 'A','B'
2. Blood groups 'A','B','O'
3. Blood groups 'AB','O'
4. Blood groups 'A','B','AB','O'
Subtopic: Co-dominance |
86%
Level 1: 80%+
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The correct statement with respect to Thalassemia in humans is:
1. \(\alpha -\)Thalassemia is controlled by a single gene HBB.
2. The gene for \(\alpha -\)Thalassemia is located on chromosome-16.
3. \(\beta -\)Thalassemia is controlled by two closely linked genes HBA-1 and HBA-2.
4. In \(\beta-\)Thalassemia the production of \(\alpha -\)globin chain is affected.
1. \(\alpha -\)Thalassemia is controlled by a single gene HBB.
2. The gene for \(\alpha -\)Thalassemia is located on chromosome-16.
3. \(\beta -\)Thalassemia is controlled by two closely linked genes HBA-1 and HBA-2.
4. In \(\beta-\)Thalassemia the production of \(\alpha -\)globin chain is affected.
Subtopic: Mendelian Disorders: Thalassemia |
83%
Level 1: 80%+
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Chromosomal aberrations are caused by:
1. Change in the structure of the gene
2. Change in the number of chromosomes
3. Change in the arrangement or position of genes
4. Change in the number or arrangement of genes in the chromosomes
1. Change in the structure of the gene
2. Change in the number of chromosomes
3. Change in the arrangement or position of genes
4. Change in the number or arrangement of genes in the chromosomes
Subtopic: Non - Disjunction & Aneuploidy |
55%
Level 3: 35%-60%
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1:2:1 phenotypic and genotypic ratio is found in:
1. Complementary genes.
2. Pseudo alleles.
3. Blending inheritance
4. Multiple alleles.
1. Complementary genes.
2. Pseudo alleles.
3. Blending inheritance
4. Multiple alleles.
Subtopic: Monohybrid Cross: Further Understanding |
55%
Level 3: 35%-60%
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