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Q. No.In eukaryotes if the gene expression is being regulated at the processing level, it means:
1.
formation of primary transcript is being regulated
2.
splicing of RNA is being regulated
3.
transport of mRNA through nuclear pores is being regulated
4.
the formation of initiation complex at the ribosome is being regulated
Subtopic: Gene Regulation in Eukaryotes |
64%
Level 2: 60%+
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Which of the following is synthesized constitutively in an E.coli cell?
1. Beta galactosidase
2. Permease
3. Transacetylase
4. Repressor of lac Operon
1. Beta galactosidase
2. Permease
3. Transacetylase
4. Repressor of lac Operon
Subtopic: Gene Regulation: Lac Operon |
67%
Level 2: 60%+
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Alec Jeffreys pioneered the technique for:
1. DNA profiling
2. Amplification of DNA
3. Separation of DNA fragments in gel electrophoresis
4. Artificial synthesis of gene
1. DNA profiling
2. Amplification of DNA
3. Separation of DNA fragments in gel electrophoresis
4. Artificial synthesis of gene
Subtopic: DNA Fingerprinting |
70%
Level 2: 60%+
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The ‘chain termination method’ for genome sequencing was developed by:
1. Hargobind Khorana
2. Fred Sanger
3. Marshall Nirenberg
4. Severo Ochoa
1. Hargobind Khorana
2. Fred Sanger
3. Marshall Nirenberg
4. Severo Ochoa
Subtopic: Human Genome Project |
77%
Level 2: 60%+
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The untranslated regions:
| I: | are present at only the 5’ end of the mature mRNA in eukaryotes |
| II: | are not required during translation and hence are spliced out of the mature mRNA |
| 1. | Only I is correct |
| 2. | Only II is correct |
| 3. | Both I and II are correct |
| 4. | Both I and II are incorrect |
Subtopic: Translation |
63%
Level 2: 60%+
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The tRNA molecule:
| 1. | looks like an inverted L in its secondary structure |
| 2. | is the largest of the major cellular RNAs |
| 3. | acts as an adapter molecule |
| 4. | has catalytic functions |
Subtopic: Translation |
80%
Level 1: 80%+
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In bacteria:
| 1. | translation can begin before the mRNA is fully transcribed |
| 2. | removal of introns from hnRNA is carried out by ribozymes |
| 3. | there are at least three different RNA polymerases to transcribe different RNA molecules |
| 4. | the transcription of mRNA takes place in a template independent manner |
Subtopic: Transcription |
77%
Level 2: 60%+
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Identify the incorrectly matched pair:
| 1. | Taylor | Radioactive thymidine |
| 2. | Meselson and Stahl | 15N |
| 3. | Hershey and Chase | 32P and 35S |
| 4. | Griffith | 14C |
Subtopic: Search for Genetic Material |
89%
Level 1: 80%+
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The two polynucleotide strands in a dsDNA molecule are:
| 1. | parallel and identical |
| 2. | anti-parallel and identical |
| 3. | parallel and complementary |
| 4. | anti-parallel and complementary |
Subtopic: DNA Double Helix |
91%
Level 1: 80%+
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The allele of a gene locus that is least frequent, in a population, has a frequency greater than 0.01. Such a gene locus will be called:
| 1. | Redundant | 2. | Degenerate |
| 3. | Polymorphic | 4. | Hot spot |
Subtopic: DNA Fingerprinting |
84%
Level 1: 80%+
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