The untranslated regions:
I: are present at only the 5’ end of the mature mRNA in eukaryotes
II: are not required during translation and hence are spliced out of the mature mRNA
 
1. Only I is correct
2. Only II is correct
3. Both I and II are correct
4. Both I and II are incorrect

Subtopic:  Translation |
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Level 2: 60%+
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The tRNA molecule:
1. looks like an inverted L in its secondary structure
2. is the largest of the major cellular RNAs
3. acts as an adapter molecule
4. has catalytic functions
Subtopic:  Translation |
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In bacteria:
1. translation can begin before the mRNA is fully transcribed
2. removal of introns from hnRNA is carried out by ribozymes
3. there are at least three different RNA polymerases to transcribe different RNA molecules
4. the transcription of mRNA takes place in a template independent manner
Subtopic:  Transcription |
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Identify the incorrectly matched pair:
1. Taylor Radioactive thymidine
2. Meselson and Stahl 15N
3. Hershey and Chase 32P and 35S
4. Griffith 14C
Subtopic:  Search for Genetic Material |
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The two polynucleotide strands in a dsDNA molecule are:
 
1. parallel and identical
2. anti-parallel and identical
3. parallel and complementary
4. anti-parallel and complementary
Subtopic:  DNA Double Helix |
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The allele of a gene locus that is least frequent, in a population, has a frequency greater than 0.01. Such a gene locus will be called:
1. Redundant 2. Degenerate
3. Polymorphic 4. Hot spot
Subtopic:  DNA Fingerprinting |
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In the human genome:
1. there are 3164.7 billion base pairs
2. largest known gene is HbS
3. more than 20 percent part codes for proteins
4. chromosome 1 has most genes
Subtopic:  Human Genome Project |
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In an operon:
I: a polycistronic structural gene is regulated by a common promoter and regulatory genes
II: the regulation is always negative and inducible
 
1. Only I is correct
2. Only II is correct
3. Both I and II are correct
4. Both I and II are incorrect
Subtopic:  Gene Regulation: Lac Operon |
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The bacterium Escherichia coli was not used by:
 
1. Fred Griffith, when he discovered bacterial transformation
2. Alfred Hershey and Martha Chase, when they conclusively proved that DNA is the molecule that stores genetic information
3. Matthew Meselson and F. Stahl, when they experimentally proved that DNA replicates semi-conservatively
4. Francois Jacob and Jacques Monod, when they proposed the working of lactose operon
Subtopic:  Search for Genetic Material |
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All the following statements regarding histones, the proteins used in packaging of DNA, are correct except:

1. They are rich in amino acids - Lysine and Arginine.
2. They carry a positive charge on the side chain.
3. They are organized to form a unit of 8 molecules.
4. The pH of histones is slightly acidic.
Subtopic:  DNA Packaging |
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Level 1: 80%+
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