Q. No.Some of the steps of DNA fingerprinting are given below. Identify their correct sequence from the options given.
A. Electrophoresis of DNA fragments
B. Hybridisation with DNA probe
C. Digestion of DNA by restriction endonucleases
D. Autoradiography
E. Blotting of NDA fragments to nitrocellulose membrane
(1) C – A – B – E – D
(2) C – A – E – B – D
(3) A – E – C – B – D
(4) A – C – E – D – B
If the sequence of bases in the coding strand of a double stranded DNA is 5’-GTTCGAGTC-3’, the sequence of bases in its transcript will be
(1) 5’-GACUCGAAC-3’
(2) 5’-CAAGCUCAG-3’
(3) 5’-GUUCGAGUC-3’
(4) 5’-CUGAGCUUG-3’
Refer to the given figure and select the correct option regarding its parts labelled as A, B and C.
(1) A-Histone octamer, C-DNA
(2) B-H1 histone, C-Histone octamer
(3) A-H1 histone, B-DNA
(4) A-Histone octamer, C-H1 histone
Match the triplet codons listed in column I with their amino acids mentioned in column II and select the correct option from the given codes.
|
Column I |
Column II |
|
A. GGG |
(i) Proline |
|
B. UUU |
(ii) Glycine |
|
C. CCC |
(iii) Arginine |
|
D. AAA |
(iv) Phenylalanine |
|
|
(v) Lysine |
(1) A-(v), B-(iii), C-(i), D-(ii)
(2) A-(v), B-(iii), C-(i), D-(iv)
(3) A-(ii), B-(iv), C-(i), D-(v)
(4) A-(i), B-(ii), C-(iii), D-(iv)
Match the following column
|
Column I |
Column II |
|
I. Multigenes |
(i) transposons |
|
II. Inducible genes |
(ii) insulin |
|
III. Overlapping genes |
(iii) B, E and k in × 174 |
|
IV. Structural genes |
(iv) snRNA |
|
|
(v) globin gene |
|
|
(vi) nitrate reductase |
|
|
I |
II |
III |
IV |
|
(1) |
(i) |
(iii) |
(v) |
(ii) |
|
(2) |
(v) |
(vi) |
(iii) |
(ii) |
|
(3) |
(iv) |
(v) |
(vi) |
(i) |
|
(4) |
(i) |
(ii) |
(v) |
(vi) |
The premature termination of polypeptide synthesis due to stop codon can be overcome via compensatory mutation in tRNA. This genetic phenomenon is called
(1) extragenic suppression
(2) intragenic suppression
(3) codon bias
(4) true reversion
Suppose, evolution on earth had occurred in such a way that there are 96 amino acids instead of 20. DNA has 12 different types of bases and DNA synthesis occurs in the same way as today. The minimum number of bases per DNA codon would be
(1) 12
(2) 8
(3) 2
(4) 3
Radioactive thymidene is fed to cells about to enter S-phase. It will make radioactive
(1) euchromatin
(2) heterochromatin
(3) Both (1) and (2)
(4) neither euchromatin nor heterochromatin
What would happen, if in a gene encoding a polypeptide of 50 amino acids, 25th codon (UAU) is mutated to UAA?
(1) A polypeptide of 49 amino acids will be formed
(2) A polypeptide of 25 amino acids will be formed
(3) A polypeptide of 24 amino acids will be formed
(4) Two polypeptides of 24 and 25 amino acids will be formed
Which one of the following set meaning is not different?
|
(1) Cistron |
– |
Triplet |
|
(2) DNA profile |
– |
DNA type |
|
(3) Gene pool |
– |
Genome |
|
(4) Gene |
– |
Codon |
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