Match each item in Column I with one item in Column II and chose your answer from the codes given below:

Column I

Disorder

Column II

Feature

I. Phenylketonuria

II. Sickle Cell anemia

III. Down's Syndrome

IV. Turner's Syndrome

(i) Rudimentary ovaries

(ii) Gynecomastia

(iii) Trisomy 21

(iv) Lack of enzyme PAH

(v) Lack of tyrosinase

(vi) Mutation GAG to GUG

(vii) Mutation GUG to GAG

 

1. I - v; II - vii; III - iii; IV - i

2. I - iv; II - vi; III - iii; IV - i

3. I - v; II - vi; III - iii; IV - ii

4. I - v; II - vi; III - iii; IV - i

Subtopic:  Mendelian Disorders |
 60%
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In a monohybrid cross F1 progeny resemble neither of the parents. What would be true in this case?

1. The parental traits would not appear in any of the F2 -progenies

2. The F2 phenotypic ratio will be different from the F2 genotypic ratio

3. It could be a case of incomplete dominance

4. The F2 phenotypic ratio will be similar to any Mendelian monohybrid cross

Subtopic:  Monohybrid Cross: 1 |
 76%
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The two alleles of a gene pair are located on:

1. Homologous sites on homologous chromosomes

2. Heterologous sites on homologous chromosomes

3. Homologous sites on heterologous chromosomes

4. Heterologous sites on heretologous chromosomes

Subtopic:  Chromosomal Basis of Inheritance: Further Considerations |
 76%
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Male heterogamety is not seen in:

1. Humans

2. Melandrium album

3. Birds

4. Fruit fly

Subtopic:  Sex Determination: Further Considerations |
 82%
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The trait shown in the given pedigree chart is most likely a/an:

1. Autosomal recessive trait

2. Autosomal dominant trait

3. Sex linked recessive trait

4. Sex linked dominant trait

Subtopic:  Pedigree Analysis: Problem Solving |
 79%
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Aneuploidy results from :

1. Point mutations

2. Gross structural changes in chromosomes

3. Failure of cytokinesis after telophase stage of cell division

4. Failure of segregation of chromatids during cell division 

Subtopic:  Non - Disjunction & Aneuploidy |
 66%
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Which of the following are correct regarding linked genes?

I. are located near each other on the same chromosome.

II. violate the law of independent assortment

III. segregate together during meiosis

(1) Only I and II

(2) Only I and III

(3) Only II and III

(4) I, II, III

Subtopic:  Linkage |
 57%
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Consider the cross AaBb x AaBb. If the alleles for both genes exhibit complete dominance, what genotypic ratio is expected in the resulting offspring?

1. 1:1:1:1

2. 9:3:3:1

3. 3:6:3:1:2:1

4. 1:2:1:2:4:2:1:2:1

Subtopic:  Dihybrid Cross Analysis |
 64%
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Two phenotypically normal individuals have an affected child. What can we conclude about the parents?

1. they both carried the diesease allele

2. they are not the parents of the child

3. they are affected

4. no conclusions can be drawn

Subtopic:  Mendelian Disorders |
 86%
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What is the basis of pleiotropy?

1. A spontaneous mutation during the replication of DNA.

2. Interrelationship between various metabolic pathways in the body.

3. Chromosomal aberration as chromosomes are the vehicles of genes.

4. the behaviour of chromosomes during meiosis or gamete formation.

Subtopic:  Polygenic Inheritance & Pleiotropy |
 55%
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