| I: | Gene therapy involves the introduction of a functional gene into the cells of an individual to treat genetic disorders. | 
| II: | RNA interference (RNAi) is a technique used to silence specific genes by degrading their structural genes located on template DNA. | 
| III: | Transgenic organisms are those that have been genetically modified to express desirable traits. | 
| Assertion (A): | Gene therapy is a method of treating a disorder but cannot cure it. | 
| Reason (R): | Cells are drawn from a patient and the functional gene is introduced into these cells and transferred back to the patient. | 
| 1. | Both (A) and (R) are True and (R) is the correct explanation of (A). | 
| 2. | Both (A) and (R) are True and (R) is not the correct explanation of (A). | 
| 3. | (A) is True but (R) is False. | 
| 4. | (A) is False but (R) is True. | 
Consider the given two statements:
| Assertion (A): | Gene therapy for ADA deficiency can provide a permanent cure. | 
| Reason (R): | Inserting a functional ADA gene into a patient's circulating lymphocytes cells enables the production of the enzyme for entire life of the patient. | 
| 1. | Both (A) and (R) are True and (R) is the correct explanation of (A). | 
| 2. | Both (A) and (R) are True but (R) is not the correct explanation of (A). | 
| 3. | (A) is True but (R) is False. | 
| 4. | Both (A) and (R) are False. |