Thalassemia is inherited as a/an ____________ condition.
1. | Autosomal recessive | 2. | Autosomal dominant |
3. | Sex linked recessive | 4. | Sex linked dominant |
1. | The former is a quantitative problem of synthesising too few globin molecules while the latter is a qualitative problem of synthesising an incorrectly functioning globin. |
2. | The former is a qualitative problem of synthesising too few globin molecules while the latter is a quantitative problem of synthesising an incorrectly functioning globin. |
3. | Both disorders are qualitative problems of synthesising too few globin molecules. |
4. | Both disorders are quantitative problems of synthesising too few globin molecules. |
Assertion (A): | Both α- and β-thalassemias are often inherited in an autosomal recessive manner. |
Reason (R): | The thalassemias are classified according to which chain of the hemoglobin molecule is affected. |
1. | Both (A) and (R) are True and (R) correctly explains (A) |
2. | Both (A) and (R) are True but (R) does not correctly explain (A) |
3. | (A) is True, (R) is False |
4. | (A) is False, (R) is True |