| Assertion(A): | The pattern of inheritance of Mendelian disorders can be traced in a family by the pedigree analysis. |
| Reason(R): | Mendelian disorders are mainly determined by alteration or mutation in a single gene with complete dominance. |
| 1. | (A) is False but (R) is True. |
| 2. | Both (A) and (R) are True and (R) is the correct explanation of (A). |
| 3. | Both (A) and (R) are True but (R) is not the correct explanation of (A). |
| 4. | (A) is True but (R) is False. |
Mendelian disorders are mainly determined by:
| 1. | Alteration or mutation in a single gene. |
| 2. | Chromosomal gross structural changes. |
| 3. | Recombination between linked genes. |
| 4. | Jumping genes |
What is the mode of inheritance of phenylketonuria?
| 1. | Autosomal recessive | 2. | Autosomal dominant |
| 3. | Sex linked recessive | 4. | Sex linked dominant |
In cases of Phenylketonuria:
| 1. | The affected individual lacks an enzyme that converts the amino acid tyrosine into phenylalanine. |
| 2. | The affected individual makes an enzyme that converts the amino acid tyrosine into phenylalanine. |
| 3. | The affected individual makes an enzyme that converts the amino acid phenylalanine into tyrosine. |
| 4. | The affected individual lacks an enzyme that converts the amino acid phenylalanine into tyrosine. |
| Assertion(A): | Patients of phenylketonuria can show mental retardation. |
| Reason(R): | Phenylpyruvic acid can get accumulated in the brain of the patients suffering from phenylketonuria. |
| 1. | (A) is True but (R) is False |
| 2. | (A) is False but (R) is True |
| 3. | Both (A) and (R) are True and (R) is the correct explanation of (A) |
| 4. | Both (A) and (R) are True but (R) is not the correct explanation of (A) |
| Assertion(A): | A simple treatment for children suffering from phenylketonuria can be diet restrictions. |
| Reason(R): | Phenylalanine is an essential amino acid. |
| 1. | Both (A) and (R) are True and (R) is the correct explanation of (A). |
| 2. | Both (A) and (R) are True but (R) is not the correct explanation of (A). |
| 3. | (A) is True but (R) is False. |
| 4. | (A) is False but (R) is True. |
Consider the following two statements:
| Statement I: | Phenylketonuria is an autosomal recessive disorder |
| Statement II: | Phenylketonuria is an inborn error of metabolism |
1. Only Statement I is correct
2. Only Statement II is correct
3. Both Statement I and Statement II are correct
4. Both Statement I and Statement II are incorrect