Under conditions where methionine must be the first amino acid, what protein would be coded for by the following mRNA?

5'-CCUCAUAUGCGCCAUUAUAAGUGACACACA-3'

1. pro his met arg his tyrlyscys his thr
2. met arg his tyrlyscys his thr
3. met arg his tyrlys
4. met pro his met arg his tyrlyscys his thr
Subtopic:  Translation |
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Which of the following pairs of codons encode the same amino acid?

1.AUG and AUC2.UAA and UAC
3.GUA and GUG4.UAG and UAC

Subtopic:  Translation |
 60%
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The amino acid sequence for a eukaryotic gene is placed in a plasmid just downstream of a promoter. Which of the following can be the most likely result?

1. The cell would die because of the antigenicity of the eukaryotic proteins.
2. The prokaryotic cell will demonstrate the eukaryotic processes such as splicing.
3. An mRNA would form, but would it would be much longer than that formed directly from the template in the original eukaryote.
4. If the ribosome could bind the mRNA, a polypeptide that is longer than the one from the original eukaryote would be created.
Subtopic:  Translation |

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Hints

Identify the correct statements from the given statements and choose the correct option:

I: Both prokaryotic and eukaryotic mRNAs have a 5' cap.
II: Only prokaryotic mRNAs are polyadenylated at the 3' end.
III: In prokaryotes, transcription is coupled to translation.
IV: In eukaryotes, RNA splicing occurs after the mRNA is transported into the cytoplasm.
V: RNA splicing requires the formation of a spliceosome.
VI: Both prokaryotic and eukaryotic mRNAs are synthesized by RNA polymerase.

1. III, V, and VI only
2. II, III, V, and VI only
3. I, III, V, and VI only
4. I, III, IV, V, and VI only
Subtopic:  Transcription: I | Translation | Translation Mechanism |
 65%
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The correct chronological order of the steps of translation of a prokaryotic mRNA will be:

I:  attachment of the initiator tRNA onto the start codon
II:  binding of the mRNA to small ribosome subunit of a ribosome
III:  attachment of the large ribosome subunit to the mRNA
IV:  translocation of the ribosome to move a new codon to be in the A site
V:  entry of a charged tRNA into the A site
 
1. I II V III IV
2. II I III V IV
3. I II III V IV
4. II I IV III V

Subtopic:  Translation |
 63%
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Consider the following statements:

I: The cellular factory responsible for synthesizing proteins is the ribosome.
II: The ribosome also acts as a catalyst for the formation of a peptide bond.
III: The UTRs (untranslated regions) in an mRNA are not required for translation.


Which of the above statements are true?

1. I and II only 2. I and III only
3. II and III only 4. I, II, and III

Subtopic:  Translation |
 71%
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With regard to mature mRNA in eukaryotes:

1. exons and introns do not appear in the mature RNA.
2. exons appear but introns do not appear in the mature RNA.
3. introns appear but exons do not appear in the mature RNA.
4. both exons and introns appear in the mature RNA.
Subtopic:  Translation | Translation Mechanism |
 87%
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In translation, the enzyme amino acyl-tRNA synthetase:

1.  synthesizes tRNA
2.  attaches amino acids to tRNA
3.  hydrolyzes excess tRNA molecules
4.  helps tRNA synthesize amino acids

Subtopic:  Translation |
 70%
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