| 1. | They were partially isolated from the surroundings |
| 2. | They could maintain an internal environment |
| 3. | They were able to reproduce |
| 4. | They could separate combination of molecules from the surroundings |
| 1. | Haldane | : | Hot dilute soup |
| 2. | Oparin | : | Coacervate |
| 3. | Fox | : | Microspheres |
| 4. | Spallanzani | : | Abiogenesis |