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Oxytocin helps in 
1. Ovulation
2. Lactation but not childbirth
3. Childbirth but not lactation
4. Lactation and Childbirth both

Which of the following are not steroid hormones but still do not act through second messenger system, are small, nonpolar and can be taken orally?
1. prostaglandins
2. estrogen and progesterone
3. insulin and glucagon
4. thyroid hormones (T3 and T4)

Which of the following regulates carbohydrate, protein and lipid metabolism in a manner opposite to that of insulin?
1. Glucagon
2. Cortisol
3. Epinephrine
4. Norepinephrine

Hypocalcemia may lead to:-
1. Kidney stones
2. Cholelithiasis
3. Stronger muscle contractions
4. Tetany

Glucocorticoids do not:
1. Stimulate gluconeogenesis
2. Cause lipolysis
3. Cause proteolysis
4. Stimulate cellular uptake and utilization of amino acids

Which hormone stimulates exocrine pancreas to secrete water and bicarbonate ions?
1. Gastrin
2. Cholecystokinin
3. Secretin
4. Gastric inhibitory peptide

A hormone that has intracellular receptors would be 
1. ACTH
2. ADH
3. Melatonin
4. Aldosterone

The immune responses in older people are weak due to the degeneration of:
1. Thyroid
2. Pineal
3. Adrenal
4. Thymus

Which of the following is true?
1. Hormones regulate cellular functions, and generally negative feedback regulates hormone levels.
2. The circulating level of a hormone is held constant through a series of positive feedback loops.
3. Both lipid-soluble hormones and water soluble hormones bind to intracellular protein receptors.
4. The ducts of endocrine organs release their contents into the bloodstream.

Identify the incorrect statement:
1. In males FSH regulates spermatogenesis
2. Thyroid gland produces T3 and thyroxine (T4) hormones
3. ACTH stimulates secretion of glucocorticoids
4. PTH is a hyperglycemic hormone

The amino acid derivative among the following hormone is:-
1. Insulin
2. Epinephrine
3. Estradiol
4. Testosterone

Androgenic steroids in females are secreted by:
1. pineal gland
2. Testes
3. Adrenal cortex
4. Hypothalamus

Hyperthyroidism [Graves' disease] is characterized by all the following except:
1. Toxic goiter
2. Exopthalmos
3. Bradycardia
4. Muscle weakness and termors

ACTH controls the secretion of:
1. cortisol
2. aldosterone
3. epinephrine
4 testosterone

Hypersecretion of growth hormone in adults does not cause further increase in height because 
1. growth hormone becomes inactive in adults
2. epiphyseal plates close after adolescence 
3. bones loose their sensitivity to growth hormone in adults 
4. muscle fibres do not grow in size after birth 

Graves disease is caused due to?
1. hyposecretion of thyroid gland
2. hypersecretion of thyroid gland
3. hyposecretion of adrenal gland
4. hypersecretion of adrenal gland

The posterior pituitary gland is not a ‘true’ endocrine gland because.
1. it is provided with a duct
2. it only stores and releases hormones
3. it is under the regulation of hypothalamus
4. it secretes enzymes

Which of the following pairs of hormones are not antagonistic (having opposite effects) to each other?
1. Insulin               Thyroid hormone
2. Aldosterone       Atrial Natriuretic Factor
3. Relaxin              Inhibin
4. Parathormone   Calcitonin

A pregnant female delivers a baby, who suffers from stunted growth mental retardation low intelligence quotient and abnormal skin. This is the result of
1. deficiency of iodine in diet
2. low secretion of growth hormone
3. cancer of the thyroid gland
4. over secretion of pars distalis

Which of the following statement is correct in relation to the endocrine system?
1. Adenohypophysis is under direct neural regulation of the hypothalamus
2. Organs in the body like gastrointestinal tract. heart, kidney and liver do not produce any hormones
3. Non-nutrient chemicals produced by the body in trace amount that act as intercellular messenger are known as hormones
4. Releasing and inhibitory hormones are produced by the pituitary gland

What is correct to say about the hormone action in humans?
1. Glucagon is secreted by $\mathrm{\beta }$-cells of islets of Langerhans and stimulates glycogenolysis
2. Secretion of thymosine is stimulated with ageing.
3. In females, FSH first binds with specific receptors on ovarian cell membrane
4. FSH stimulates the secretion of oestrogen and progesterone

Match the source gland with its respective hormone as well as the function.

Injury to adrenal cortex is not likely to affect the secretion of which one of the following ?
1. Aldosterone
2. Both androstenedione and dehydroepiandrosterone
3. Adrenalin
4. Cortisol

Toxic agents present in food which interfere with thyroxin synthesis lead to the development of 
1. toxic goitre
2. cretinism
3. simple goitre
4. thyrotoxicosis

A health disorder that results from the deficiency of thyroxine in adults and characterized by 
(i) a low metabolic rate
(ii) increase in body weight
(iii) tendency to retain water in tissues is 
1. hypothyroidism
2. simple goitre
3. myxoedema
4. cretinism

The blood calcium level is lowered by the deficiency of ?
1. parathormone
2. thyroxine
3. calcitonin
4. Both 1. and 2.

A person is having problems with calcium and phosphorus metabolism in his body. Which one of the following glands may not be functioning properly?
1. Parathyroid
2. Parotid
3. Pancreas
4. Thyroid

Compared to a bull, a bullock is docile because of:
1. higher levels of thyroxin
2. higher levels of cortisone
3. lower levels of blood testosterone
4. lower levels of adrenalin/noradrenalin in its blood

Sertoli cells are regulated by the pituitary hormone known as:
1. FSH
2. GH
3. Prolactin 
4. LH

Which one of the following is not a second messenger in hormone action ?
1. cGMP                 
2. Calcium
3. Sodium               
4. cAMP

Which of the following is an accumulation and release centre of neurohormones?
1. Posterior pituitary lobe
2. Intermediate lobe of the pituitary
3. Hypothalamus 
4. Anterior pituitary lobe

Which hormone causes dilation of blood vessels, increased oxygen consumption and gluco-genesis ?
1. ACTH
2. Insulin
3. Adrenalin
4. Glucagon

Which is not a symptom of hyperglycaemia?
1. Loss of weight
2. Breakdown of muscle tissue
3. High blood glucose level
4. Diplopia

Which of the following is a prolactin-inhibiting hormone secreted in the hypothalamus ?
1. Serotonin 
2. Dopamine
3. Epinerphrine
4. Histamine 

All hypophysiototropic hormones are peptides except
1. corticotropin releasing hormone
2. growth hormone
3. somatostatin
4. prolactin release inhibiting hormone.

Sella Turcica is found 
1. in bones
2. in joints
3. nearby pituitary
4. nearby thyroid

The source of somatostatin is same as that of
1. thyroxine and calcitonin
2. insulin and glucagon
3. somatotropin and prolactin 
4. vasopressin and oxytocin.

Which one of the following four glands is correctly matched with the accompanying description?
1. Thyroid - hyperactivity in young children causes cretinism
2. Thymus - starts undergoing atrophy after puberty
3. Parathyroid - secrets parathormone which promotes movement of calcium ions from blood into bones during calcification
4. Pancreas - Delta cells of the Islets of Langerhans secrete a hormone which stimulates glycolysis in liver

A patient of diabetes mellitus excretes glucose in urine even when he is kept in a carbohydrate free diet. It is because:-
1. fats are catabolised in adipose tissues to form glucose
2. amino acids are catabolised in kidney to form glucose
3. amino acids are discharged in blood stream from liver
4. glycogen from muscles is released in blood stream

Match the source gland with its respective hormone and function and select the correct option.
       Source gland             Hormone          Function
1.  Anterior pituitary         Oxytocin          Contraction of uterine muscles
2. Anterior pituitary          Vasopressin      Induces reabsorption of water in nephron 
3. Thymus                      Thymosin          Proliferation of T-lymphocytes 
4. $\mathrm{\alpha }$-cells of islets           Glucagon           Uptake of glucose into the cell.
     of Langerhans

Achondroplasia is a disease related with the defect in the formation of 
1. membrane
2. cartilage
3. mucosa
4. none of these

In a child of 15 years age, plasma calcium level is diagnosed below optimum level.Which organ is malfunctioning?
1. Thyroid gland
2. Liver
3. Parathyroid
4. Posterior lobe of pituitary

Assertion             :       Aldosterone increases the volume of blood and other extracellular fluids.
               
Reason     :     The secretion of aldosterone is stimulated by a fall in the circulating volume of blood.

Assertion  :     Adrenal cortex can be removed without causing death.          
Reason     :     Adrenal cortex is not vital for survival.

Assertion   :       The tadpoles become giant tadpoles when fed on thiourea.
Reason      :       Thiourea is an antithyroid substance.

Which of the following hormone is secreted by Pars nervosa?
1. Oxytocin
2. Vasopressin
3. Melanocyte
4. Both 1 and 2

Which of the following hormone induce ovulation and maintains corpus luteum?
1. FSH
2. LH
3. Both A and B
4. Estrogen

A hormone _____ which acts on   ____ of nephron and helps in reabsorption of water and
electrolytes.
1. ADH, PCT
2. ADH, DCT
3. ADH, Loop of Henle
4. None of these 

Goitre occurs in case of

Which of the following hormone is known as emergency hormone
1. Adrenaline
2. Non-adrenaline
3. Catecholamines
4. Adrenal medulla